Despera is an advisor and strategist to Grimlord who also created her. She is dressed in an elegant white robe and a horned headdress, and wields a large scepter. She is quick to lose her temper and is an immensely powerful warrior. She is the sister of Desponda. Ryan once clashed with Despera, who battled him through various dimensions. In our dimension, Despera could float and blast purple electricity from the sphere on her staff. In another dimension, Despera seemed to turn invisible and attacked by throwing her staff around like a spear. Ryan also encountered another dimension, while involved in a battle with her, that was like a giant, slowly revolving crystal ball. Ryan escaped this dimension by blasting the crystal ball walls a few times with his laser pistol. Ryan defeated Despera in battle, by tricking her into zapping a trap wall in the temple containing Grimlord's secret identity. She was struck in the shoulder by an arrow, and after removing the arrow, promptly retreated. Unlike her Japanese counterpart, she doesn't fade away after Oraclon's destruction.
In "Uchuu Keiji Shaider," Despera's Japanese equivalent is the transvestite grandson of Oraclon's Japanese equivalent, who is also second-in-command.